PIRFENIDONE
Anti-inflammatory, antioxidant and antifibrotic agent, derived from pyridines compounds.
Specification – pharmacopeia: EP
Therapeutic category: anti-inflammatory and antifibrotic agent
Treatment: for of Idiopathic pulmonary fibrosis (IPF) control.
Pharmacology: Pirfenidone acts mainly over growing factors and tumoral necrosis factors (TGF-β1 and TNF-α) where it inhibits collagen synthesis, down-regulates profibrotic cytokines and decreases fibroblast proliferation, which stops the accumulation of extracellular matrix on the lungs.
Aplicación: human
CAS number: 53179-13-8
Chemical formula: C12H11NO
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