PIRFENIDONE



Anti-inflammatory, antioxidant and antifibrotic agent, derived from pyridines compounds.

Specification – pharmacopeia: EP

Therapeutic category: anti-inflammatory and antifibrotic agent

Treatment: for of Idiopathic pulmonary fibrosis (IPF) control.



Pharmacology: Pirfenidone acts mainly over growing factors and tumoral necrosis factors (TGF-β1 and TNF-α) where it inhibits collagen synthesis, down-regulates profibrotic cytokines and decreases fibroblast proliferation, which stops the accumulation of extracellular matrix on the lungs.

Aplicación: human

CAS number: 53179-13-8

Chemical formula: C12H11NO

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