Positive inotropic agent with vasodilating activity

Specification – pharmacopeia: In House

Therapeutic category: cardiotonic

Treatment: Adjuvant for treatment of chronic cardiac insufficiency and cardiac insufficiency post-stroke.

Pharmacology: Levosimendan increases the sensibility of cardiac contractile proteins for Ca2+ ions, through Cardiac Troponin C (cTnC) binding, increasing the contractile force and opens the ATP sensitive canal in the vascular smooth muscle, allowing the vase-dilatation inside arteries.

Aplicación: human

CAS number: 141505-33-1

Chemical formula: C14H12N6O